Bio-Energetic Sequencing - 5 Phases of Cellular Rejuvenation
$20M Series A

Bio-Energetic Sequencing Model

The first dependency-gated framework for systemic age reversal. Each phase prepares the cellular environment for the next.

$600B+
Market Size
74
Citations
286
Page Protocol
3
Papers

The Dependency Chain

Sequence matters more than compounds. Each intervention enables the next.

NAD+ ENABLES Sirtuins ACTIVATES Autophagy CLEARS Senescent Cells ENABLES Regeneration

Five Phases of Cellular Rejuvenation

Each phase is backed by peer-reviewed research and maps to specific biomarkers.

Phase 1: NAD+ and Sirtuin Activation
Phase 1

Energy Restoration

NAD+ activates SIRT1, SIRT3, SIRT6 - the primary longevity sirtuins.

NAD+ NMN NR
Phase 2: Autophagy Activation
Phase 2

Cellular Cleanup

Autophagy clears damaged mitochondria and protein aggregates.

Spermidine AMPK Fasting
Phase 3: Senolytic Clearance
Phase 3

Senescent Removal

Senolytics target SASP-producing zombie cells for apoptosis.

Quercetin Fisetin D+Q
Phase 4: Stem Cell Regeneration
Phase 4

Stem Cell Reset

Mesenchymal stem cells activate in the cleared niche.

BPC-157 Exosomes GH
Phase 5: Epigenetic Optimization
Phase 5

Epigenetic Reset

Yamanaka factors and mTOR modulation reverse epigenetic age.

Rapamycin Oct4 Sox2

Built on Peer-Reviewed Science

Every intervention in our protocol is backed by published research from leading institutions.

Comprehensive Literature Analysis

Synthesized from thousands of peer-reviewed publications

74
Primary Citations
286
Protocol Pages
5
Clinical Phases

Our research synthesizes findings from Nature, Cell, Science, and specialized aging journals.

View Published Research

Computational Biology Platform

Accelerating longevity research through systematic analysis of intervention mechanisms, timing, and interactions.

Literature Synthesis

Systematic analysis of thousands of peer-reviewed papers to surface relevant findings and cross-reference molecular mechanisms.

Meta-Analysis Citation Mapping Evidence Grading

Pathway Analysis

Mapping intervention dependencies across cellular signaling cascades to validate mechanisms and identify optimal timing.

Dependency Graphs Interaction Modeling Safety Profiling

Protocol Development

Translating research findings into structured clinical protocols with defined biomarkers, dosing, and monitoring requirements.

Clinical Guidelines Biomarker Tracking Iterative Refinement

$20M to Own the Category

The longevity market is $600B+ with zero category-defining leaders. We have the scientific framework, the protocol, and the IP. Now we need capital to scale.

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Use of Funds

Clinical Validation $8M (40%)
Platform Development $5M (25%)
Regulatory Pathway $4M (20%)
Category Leadership $2M (10%)
Team Expansion $1M (5%)