Intervention Dependency Mapping
Understanding how interventions create conditions that enable or impede subsequent interventions. The goal is identifying optimal sequencing paths.
Vol. 3 — About
Mullo
Mullo
Saint
Independent Researcher
Applied Geroscience • Cellular Bioenergetics
Focused on the integration of geroscience, cellular bioenergetics, and intervention sequencing. This work advances longevity practice beyond indiscriminate compound stacking toward physiologically coherent protocols that respect cellular energy constraints.
The Bio-Energetic Sequencing Model emerged from recognizing a fundamental error in longevity practice: treating aging as a pharmacological problem requiring more compounds rather than an engineering problem requiring correct sequencing. Most interventions fail not because they're ineffective, but because they're deployed in the wrong order to energy-depleted cells.
"Aging persisted not because it was unsolvable, but because it was misclassified. This research reclassifies it—as an engineering problem with a defined solution space."
Research Focus
Cellular Energy Economics
Quantifying the bioenergetic costs of repair processes and how energy availability constrains what aged cells can accomplish.
Biomarker-Driven Protocols
Developing measurable criteria for phase transitions. No fixed timelines—advancement based on documented physiological changes.
Protocol Documentation
Creating comprehensive implementation guides that translate research findings into actionable, reproducible protocols.
What This Is / What It Isn't
Evidence-Based Framework
Research grounded in peer-reviewed literature, mechanistic reasoning, and documented biomarker changes. Claims are proportional to evidence quality.
Engineering Approach
Treating cellular rejuvenation as a systems engineering problem with defined constraints, dependencies, and measurable outcomes.
Not Medical Advice
This content is educational and does not constitute medical advice. Interventions discussed are experimental and should only be considered under qualified supervision.
Not Supplement Marketing
No financial relationships with supplement manufacturers. No affiliate links. Compound recommendations based solely on evidence and mechanistic fit.
Educational Content Only
This site publishes independent research for educational purposes only. Content has not been evaluated by regulatory authorities and does not constitute medical advice. The interventions discussed involve experimental compounds and protocols. Consult qualified healthcare professionals before considering any intervention.